Cullin family protein binding
WebCullin RING ubiquitin E3 ligases (CRL) is the largest family of ubiquitin E3 ligases. In fact, CRL is a multiprotein complex, in which cullin serves as a scaffold linking a ubiquitin … WebHere we identify Skp2 as a component of an Skp1-cullin-F-box complex that is based on a Cul1-Ro52 RING finger B-box coiled-coil motif family protein catalytic core. Ro52-containing complexes display E3 ligase activity and promote the ubiquitination of Thr187-phosphorylated p27 in a RING-dependent manner in vitro.
Cullin family protein binding
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WebMar 21, 2024 · Summary. Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation and regulation of protein ubiquitination. … Webprotein binding cullin family protein binding (GO:0097602) is_a protein binding dynein heavy chain binding (GO:0045504) is_a protein binding modification-dependent protein binding (GO:0140030) is_a protein binding growth factor binding (GO:0019838) is_a protein binding
WebMembers of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that … Web(2008) Identifying determinants of cullin binding specificity among the three functionally different Drosophila melanogaster Roc proteins via domain …
WebPredicted to enable cullin family protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within protein homooligomerization. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human … WebMay 2, 2016 · We identified that several putative miRNA target genes like Cullin 2 (CUL2), member RAS oncogene family (RAB6A), UBE2I, clathrin heavy chain 1 (CLTC), Desmocollin 3 (DSC3), Ras Family Small GTP Binding Protein (RAP1B), LSM12 homolog (LSM12), protocadherin 11 X-linked (PCDH11X) and HCLS1 Associated Protein X-1 …
WebOct 31, 2024 · Cullin (CUL) proteins have critical roles in development and cancer, however few studies on CUL7 have been reported due to its characteristic molecular …
WebDec 4, 2011 · Cullin proteins are molecular scaffolds that have crucial roles in the post-translational modification of cellular proteins involving ubiquitin. The mammalian cullin … option60是什么http://amigo.geneontology.org/amigo/term/GO:0097602 option7aWebGene ID: 83962, updated on 6-Nov-2024 Summary Predicted to enable cullin family protein binding activity and identical protein binding activity. Predicted to be involved in neurogenesis. Predicted to act upstream of or within cell differentiation and muscle organ development. Located in P-body. option888 loginWebNov 25, 2024 · The largest family of this type is the Cullin-RING E3 ligase (CRL) complex family, with over 200 members [17,18]. Within this family, the CRL1 or S phase kinase-associated protein 1 (S kp1)-C ullin 1-F-box protein (SCF) E3 ligases are the best characterized . In these ligases, the CRL scaffold, Cullin 1 (Cul1), binds the Skp1 … option92WebCullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination . portman and associates savannah gaWebIts expression is induced by heat shock. HSP47 is expressed in the endoplasmic reticulum. These cells synthesize and secrete type I and type II collagen. [7] The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. portman ageWebMay 3, 2024 · We also narrowed down the Cullin family members with the presence of both Cullin and Cullin_Nedd8 domains ... McLoughlin, F.; Vierstra, R.D. Atg8-binding uim proteins define a new class of autophagy adaptors and receptors. Cell 2024, 177, 766–781.e24. [Google Scholar] Marshall, R.S.; McLoughlin, F.; Vierstra, R.D. Autophagic … option888.com