Slp76 flow
WebbClone REA427 recognizes the human SH2 domain-containing leukocyte protein of 76 kDa (SLP-76) regardless of phosphorylation status. SLP-76 is a signal-transducing tyrosine … Webb6 sep. 2024 · In some aspects, a washing step is accomplished a semi-automated ″flow-through″ centrifuge. In some aspects, a washing step is accomplished by tangential flow filtration (TFF) . In some embodiments, the cells are resuspended in a variety of biocompatible buffers after washing, such as, for example, Ca 2+ /Mg 2+ free PBS.
Slp76 flow
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WebbA New Approach for Quantitative Phosphoproteomic Dissection of Signaling Pathways Applied to T Cell Receptor Activation Webb4 feb. 2024 · LCP2, SLP76. Specificity : human. Concentration : 1:11. Uses : For research use only. Application Summary : Intracellular flow cytometry. Storage : Store protected …
WebbSLP76 is a cytosolic adapter protein that functions as a substrate in the T cell receptor (TCR) activation pathway. Upon TCR engagement, SLP76 is phosphorylated on multiple … WebbAs Phospho SLP76 (Ser396) is a readout of T cell activation, it was used to monitor the inhibitory effect of PD-L1 recombinant protein on T cell activation. This assay was …
The amino acid sequence of the protein has a central domain with a high concentration of prolines, as well as domains at the amino-terminal and carboxy-terminal of the amino acid sequence. The PDB file 1H3H depicts the SH3 domain of GRAP2 in complex with an RSTK-containing peptide representing residues 226–235 of SLP-76. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and composed of three modular domains…
WebbSLP-76 antibody LS-C41105 is an unconjugated mouse monoclonal antibody to human SLP-76 (LCP2) (aa216-434). Validated for Flow, IP and WB. Cited in 1 publication.
Webb29 mars 2024 · T cells play a major role in adaptive immune response, and T cell dysfunction can lead to the progression of several diseases that are often associated with changes in the mechanical properties of ... can pepeoel see ur war thunder user skinWebbA specific band was detected for Phospho-Human SLP‑76/LCP2 (Y145) at approximately 76-80 kDa (as indicated) using 1 µg/mL of Mouse Anti-Human Phospho-SLP‑76/LCP2 … can peple wit cri du chat live a normal lifeWebbFlow Cytometry (Flow) 5 µL/1x10^6 cells - Visit thermofisher.com to view references and figures. Products are warranted to operate or perform substantially in conformance with published Product specifications in effect at the time of sale, as set forth in the Production documentation, specifications and/or accompanying package inserts ("Documentation"). flame print clothingWebbThe adapter protein SLP76 is a key orchestrator of T cell receptor (TCR) signal transduction. We previously identified a negative feedback loop that modulates T cell … can pepcid lower magnesiumWebbActin was used to verify equal loading (n=22). A representative image is shown. (B–C) Flow cytometry analysis of SLP76 levels in T cells and B-cells in peripheral blood samples of … can pepper cause kidney stonesWebbMesenteric vessels in the position of the congenital lymphatic in mature Slp76-null mice lacked lymphatic identity and expressed a marker of blood vessel identity. Genetic … flame pro fireplace repair new port richey flWebbA Life Sciences and Diagnostics business focused on enabling scientists and healthcare professionals to advance research, discovery and detection to improve global health … can pepcid raise blood sugar